Human follicular fluid proteome reveals association between overweight status and oocyte maturation abnormality

Table 3 Lower abundant HFF proteins in overweight status women (n = 21)

Swiss-Prot accession number	Protein name	Ratio (Mean ± SD) overweight status/normal weight
P01624	Immunoglobulin kappa variable 3–15	0.653 ± 0.095
A0A0A0MS15	Immunoglobulin heavy variable 3–49	0.646 ± 0.044
P02748	Complement component C9	0.646 ± 0.047
Q96PD5	N-acetylmuramoyl-l-alanine amidase	0.646 ± 0.071
P00338	l-lactate dehydrogenase A chain	0.632 ± 0.077
P04406	Glyceraldehyde-3-phosphate dehydrogenase	0.628 ± 0.184
P37802	Transgelin-2	0.626 ± 0.027
Q6IS14	Eukaryotic translation initiation factor 5A-1-like	0.624 ± 0.142
P18065	Insulin-like growth factor-binding protein 2	0.624 ± 0.176
A0A0J9YXX1	Immunoglobulin heavy variable 5-10-1	0.614 ± 0.034
Q99439	Calponin-2	0.605 ± 0.177
P15121	Aldose reductase	0.588 ± 0.113
P98160	Basement membrane-specific heparan sulfate proteoglycan core protein	0.581 ± 0.016
Q02383	Semenogelin-2	0.580 ± 0.009
P01036	Cystatin-S	0.563 ± 0.050
P01019	Angiotensinogen	0.531 ± 0.062
P00748	Coagulation factor XII	0.523 ± 0.036
P31948	Stress-induced-phosphoprotein 1	0.507 ± 0.045
P07195	l-Lactate dehydrogenase B chain	0.498 ± 0.070
P55072	Transitional endoplasmic reticulum ATPase	0.468 ± 0.100
Q9HC38	Glyoxalase domain-containing protein 4	0.442 ± 0.067

Annotations of altered proteins identified in HFF from the overweight status women compared with the normal weight women. Values < 0.658 (p < 0.01) correspond to lower abundance in the overweight status women group. Standard deviation (SD)

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