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Table 1 Reaction pathways enriched in blood vessels

From: Laser capture microdissection coupled mass spectrometry (LCM-MS) for spatially resolved analysis of formalin-fixed and stained human lung tissues

Pathway name/reactome pathway identifier (R-HSA)

Effect size

FDR

Set size

Collagen chain trimerization/R-HSA-8948216

2.71

1.83E−14

22

ECM proteoglycans/R-HSA-3000178

2.20

2.12E−14

36

Collagen biosynthesis and modifying enzymes/R-HSA-1650814

2.23

2.22E−11

26

Non-integrin membrane-ECM interactions/R-HSA-300171

2.36

9.69E−11

20

Molecules associated with elastic fibres/R-HSA-2129379

2.21

1.11E−10

15

Syndecan interactions/R-HSA-3000170

2.45

1.11E−10

12

Extracellular matrix organization/R-HSA-1474244

2.84

3.42E−10

10

MET activates PTK2 signaling/R-HSA-8874081

2.26

9.02E−10

15

Collagen degradation/R-HSA-1442490

2.18

3.12E−09

16

Laminin interactions/R-HSA-3000157

1.95

2.36E−08

6

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Clinical Proteomics

ISSN: 1559-0275