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Table 1 Proteins with a significant abundance difference (p-value < 0.05, log2 (fold change) > ± 0.5) between RA and SpA synovial fluid

From: Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients

RA SpA fold change (%)

p-value

Protein names

357

0.006

Myeloblastina

281

0.010

Annexin A3

270

0.050

Annexin A1

267

0.006

Phosphoglycerate kinase 1

267

0.041

Alpha-actinin-1

263

0.047

Myeloid cell nuclear differentiation antigena

247

0.022

Cathepsin Ga

236

0.011

Tubulin alpha-1A chain

234

0.017

Glucose-6-phosphate isomeraseb

232

0.035

Ras-related C3 botulinum toxin substrate 2

224

0.039

Heat shock-related 70 kDa protein 2

217

0.007

Triosephosphate isomeraseb

213

0.030

Moesin

209

0.031

Pyruvate kinaseb

208

0.036

Adenylyl cyclase-associated protein 1a

202

0.040

Glyceraldehyde-3-phosphate dehydrogenaseb

189

0.024

14-3-3 protein zeta/delta

186

0.030

Beta-2-microglobulin

179

0.026

Profilin-1

171

0.015

Phosphoglycerate mutase 1b

164

0.041

Plastin-2

160

0.037

Transgelin-2

151

0.010

Retinol-binding protein 4

145

0.026

Complement factor D

144

0.044

Transketolase

62

0.043

Serum amyloid P-component

43

0.019

Ig alpha-1 chain C region

40

0.027

Ig lambda-6 chain C region

22

0.038

Haptoglobin

  1. aProteins specific for neutrophile grunolocytes and monocytes
  2. bEnzymes involved in glycolysis