Table 2 Demographic data for CSF EV proteomic analysis

N

12

3

9

5

–

–

%male

66.7

33.3

77.8

20

0.131^a

0.236^a

Age at sampling, mean ± SD (years)

68.1 ± 12.0

51.9 ± 15.6

65 ± 10.0

52.0 ± 14.8

0.113^b

0.166^b

Age at onset, mean ± SD (years)

59.7 ± 12.4

51.0 ± 15.6

62.6 ± 10.7

–

–

0.229^b

% bulbar onset

50.0

66.7

44.4

–

–

0.545^a

Disease progression rate, median [IQR]

0.53 [0.21–0.63]

0.62 [0.37–0.83]

0.51 [0.22–0.60]

–

–

0.782^b