Accession | Name | Network* | CSF-PR score** | Datasets*** | Selected keywords from UniProt and Gene Ontology |
---|---|---|---|---|---|
P51693 | Amyloid-like protein 1 | Yes | − 50 | 1 ↑ [56] 1 – [57] | Postsynaptic function, neurite outgrowth, neuronal apoptosis |
P61769 | Beta-2-microglobulin | Yes | 60 | Component of the class I MHC, antigen presentation, innate immune response | |
P55290 | Cadherin-13 | Yes | − 75 | 1 – [25] | Cell adhesion, negative regulator of neural cell growth |
P16070 | CD44 antigen | Yes | 75 | 1 – [25] | Mediates cell–cell and cell–matrix interactions, cell migration |
P36222 | Chitinase-3-like protein 1 | 70 | 1 – [22] 1 ↓ [56] | Lectin that binds glycans, no chitinase activity, inflammatory response, macrophage differentiation | |
Q15782 | Chitinase-3-like protein 2 | 100 | Lectin that binds glycans, no chitinase activity, carbohydrate metabolic process | ||
P10645 | Chromogranin-A | − 50 | Innate immune response, defence response (fungus, bacterium), negative regulation of neuron death | ||
P12111 | Collagen alpha-3(VI) chain | Yes | 50 | Cell binding/adhesion, extracellular matrix organization | |
P02747 | Complement C1q subcomponent subunit C | Yes | 100 | Complement system, immune response | |
P00736 | Complement C1r subcomponent | Yes | 75 | 1 – [25] | Complement system, immune response |
P54764 | Ephrin type-A receptor 4 | Yes | − 100 | RTK signalling, promiscuous, prevents axonal regeneration, cell adhesion, cell signalling, repair after injury in the nervous system, axonal guiding | |
Q6MZW2 | Follistatin-related protein 4 | − 75 | 1 – [25] | Negative regulation of dendritic spine development and collateral sprouting | |
P48058 | Glutamate receptor 4 | Yes | − 50 | Excitatory synaptic transmission | |
P01591 | Immunoglobulin J chain | 67 | Links monomers of IgM or IgA, antigen binding, immune response | ||
Q92876 | Kallikrein-6 | Yes | − 60 | 1 ↑ [56] | Serine protease, Indicated in AD, regulation of axon outgrowth after injury, myelination |
P32004 | Neural cell adhesion molecule L1 | Yes | − 75 | 1 – [25] | Nervous system development, neuron–neuron adhesion, neuronal migration, axonal growth, synaptogenesis |
Q9ULB1 | Neurexin-1 | 67 | 1 – [4] | Cell surface protein, cell–cell interactions, axon guidance, signal transmission, neurotransmitter release | |
Q9P2S2 | Neurexin-2 | − 75 | 1 – [25] | Neuronal cell surface protein, cell recognition, adhesion, signalling | |
Q92823 | Neuronal cell adhesion molecule | − 75 | 1 – [25] | Neurite outgrowth. cell–cell contacts between Schwann cells and axons. formation and maintenance of the nodes of Ranvier on myelinated axons. | |
Q99983 | Osteomodulin | Yes | 75 | 1 – [25] | Biomineralization processes, cell adhesion, extracellular matrix |
Q9UHG2 | ProSAAS | Yes | − 75 | 1 – [25] | Control of the neuroendocrine secretory pathway. |
P23468 | Receptor-type tyrosine-protein phosphatase delta | Yes | − 100 | Phosphatase, pre- and post-synaptic differentiation of neurons | |
O00584 | Ribonuclease T2 | 100 | Lysosomal degradation of ribosomal RNA | ||
P13521 | Secretogranin-2 | − 57 | Neuroendocrine secretory granule protein | ||
Q6UXD5 | Seizure 6-like protein 2 | − 50 | Specialized ER function in neurons? |