| Gastric cancer patients | P | ||
---|---|---|---|---|
Total: n = 129 (%) | No PM: n = 86 (%) | PM: n = 43 (%) | ||
Age | ||||
 Mean(min–max) |  | 29–84 (59.0) | 32–81 (59.5) | 0.32 |
  ≤ 60 | 65 (50) | 46 (53) | 19 (44) |  |
  > 60 | 64 (50) | 40 (47) | 24 (56) |  |
Gender | 0.24 | |||
 Male | 84 (65) | 59 (69) | 25 (58) |  |
 Female | 45 (35) | 27 (31) | 18 (42) |  |
Weight loss | 0.001 | |||
 No change | 84 (65) | 64 (74) | 20 (47) |  |
 < 5 kg | 29 (22) | 17 (20) | 12 (27) |  |
  ≥ 5 kg | 16 (12) | 5 (6) | 11 (26) |  |
Tumor location | 0.008 | |||
 Upper 1/3 | 20 (16) | 13 (15) | 7 (16) |  |
 Middle 1/3 | 38 (29) | 24 (28) | 14 (33) |  |
 Lower 1/3 | 57 (44) | 45 (52) | 12 (27) |  |
 Mixed | 13 (10) | 4 (5) | 9 (22) |  |
 Othersa | 1 (1) | 0 (0) | 1 (2) |  |
Tumor size | 0.001 | |||
 Mean (min–max) |  | 0.5–14 (3.5) | 1–16 (5.9) |  |
  < 3 cm | 47 (36) | 40 (47) | 7 (16) |  |
  ≥ 3 cm | 82 (64) | 46 (53) | 36 (84) |  |
Histology type | 0.007 | |||
 Adenocarcinoma | 49 (38) | 41 (48) | 8 (19) |  |
 Others | 74 (57) | 45 (52) | 29 (67) |  |
 Data absent | 6 (5) | 0 (0) | 6 (14) |  |
Differentiation | 0.004 | |||
 High + moderate | 18 (14) | 18 (21) | 0 (0) |  |
 Poor | 105 (81) | 68 (79) | 37 (86) |  |
 Data absent | 6 (5) | 0 (0) | 6 (14) |  |
Lauren classification | 0.008 | |||
 Intestinal | 34 (26) | 30 (35) | 4 (9) |  |
 Diffuse | 41 (32) | 23 (27) | 18 (42) |  |
 Mixed | 46 (36) | 29 (34) | 17 (37) |  |
 Data absent | 8 (6) | 4 (5) | 4 (9) |  |
CEA | 0.08 | |||
  Mean (min–max) |  | 0.2–55.9 (3.4) | 0.4–372.8 (17.4) |  |
   < 5 ng/mL | 105 (81) | 73 (85) | 32 (74) |  |
  ≥ 5 ng/mL | 22 (17) | 11 (13) | 11 (26) |  |
  Data absent | 2 (2) | 2 (2) | 0 (0) |  |
CA19-9 | < 0.001 | |||
  Mean (min–max) |  | 0.6–2501 (41.9) | 0.6–1000 (437.4) |  |
    < 37 U/mL | 105 (81) | 80 (93) | 25 (58) |  |
   ≥ 37 U/mL | 21 (16) | 6 (7) | 15 (35) |  |
   Data absent | 3 (2) | 0 () | 3 (7) |  |
CA125 | < 0.001 | |||
  Mean (min–max) |  | 3.4–49.1 (13.0) | 7.5–129.3 (35.2) |  |
   < 35 U/mL | 101 (78) | 76 (88) | 25 (58) |  |
   ≥ 35 U/mL | 19 (15) | 6 (7) | 13 (30) |  |
   Data absent | 9 (7) | 4 (5) | 5 (12) |  |
CA724 | 0.002 | |||
  Mean (min–max) |  | 0.8–84.6 (5.9) | 0.9–300 (34.9) |  |
   < 10 U/mL | 88 (68) | 68 (79) | 20 (47) |  |
   ≥ 10 U/mL | 26 (20) | 12 (14) | 14 (33) |  |
   Data absent | 15 (12) | 6 (7) | 9 (20) |  |
AFP | 0.16 | |||
  Mean (min–max) |  | 0.2–11.5 (2.4) | 1–15.3 (3.8) |  |
   < 20 ng/mL | 119 (92) | 80 (93) | 39 (91) |  |
   ≥ 20 ng/mL | 1 (1) | 0 (0) | 1 (2) |  |
   Data absent | 9 (7) | 6 (7) | 3 (7) |  |
Neutrophil count | 0.36 | |||
 Mean (min–max) |  | 1.6–16.2 (3.8) | 1.6–7.9 (3.9) |  |
  < 2.5 * 10–9/L | 27 (21) | 20 (23) | 7 (16) |  |
   ≥ 2.5 * 10–9/L | 102 (79) | 66 (77) | 36 (84) |  |
Lymphocyte count | 0.001 | |||
  Mean (min–max) |  | 1.1–3.7 (1.79) | 0.6–2.7 (1.46) |  |
    < 2.0 * 10–9/L | 94 (73) | 55 (64) | 39 (91) |  |
   ≥ 2.0 * 10–9/L | 35 (27) | 31 (36) | 4 (9) |  |
NLR | 0.006 | |||
 Mean (min–max) |  | 0.7–16.2 (2.4) | 0.9–11.3 (2.9) |  |
    < 2.0 | 64 (50) | 50 (58) | 14 (33) |  |
   ≥ 2.0 | 65 (50) | 36 (42) | 29 (67) |  |
Haemoglobin | 0.003 | |||
 Mean (min–max) |  | 52–160 (126.2) | 74–159 (113.7) |  |
   < 133 g/L | 79 (61) | 45 (52) | 34 (79) |  |
   ≥ 133 g/L | 50 (39) | 41 (48) | 9 (21) |  |
Platelet count | 0.19 | |||
 Mean (min–max) |  | 96–419 (233.5) | 96–505 (234.4) |  |
  < 202 * 10–9/L | 43 (33) | 32 (37) | 11 (26) |  |
  ≥ 202 * 10–9/L | 86 (67) | 54 (63) | 32 (74) |  |
Albumin | 0.009 | |||
 Mean (min–max) |  | 29–49 (39.6) | 30–47 (38.9) |  |
   < 37 g/L | 38 (29) | 19 (22) | 19 (44) |  |
   ≥ 37 g/L | 91 (71) | 67 (78) | 24 (56) |  |
Pre-albumin | < 0.001 | |||
 Mean (min–max) |  | 0.14–0.42 (0.25) | 0.09–0.35 (0.21) |  |
   < 0.21 g/L | 37 (29) | 15 (17) | 22 (51) |  |
    ≥ 0.21 g/L | 92 (71) | 71 (83) | 21 (49) |  |
H6N5L1E1: m/z 2620.93 | < 0.001 | |||
 Mean (min–max) |  | 0.001–0.048 (0.006) | 0.002–0.020 (0.007) |  |
    < 0.0038 | 49 (38) | 43 (50) | 6 (14) |  |
    ≥ 0.0038 | 80 (62) | 43 (50) | 37 (86) |  |
H5N5F1E2: m/z 2650.98 | < 0.001 | |||
 Mean (min–max) |  | 0.001–0.028 (0.003) | 0.002–0.013 (0.004) |  |
    < 0.0017 | 33 (26) | 32 (37) | 1 (2) |  |
    ≥ 0.0017 | 96 (74) | 54 (63) | 42 (98) |  |
H6N5E2: m/z 2666.96 | < 0.001 | |||
 Mean (min–max) |  | 0.004–0.008 (0.003) | 0.002–0.010 (0.004) |  |
   < 0.0020 | 42 (33) | 39 (45) | 3 (7) |  |
   ≥ 0.0020 | 87 (67) | 47 (55) | 40 (93) |  |
H6N5L1E2: m/z 2940.08 | < 0.001 | |||
 Mean (min–max) |  | 0.001–0.073 (0.010) | 0.003–0.031 (0.013) |  |
  < 0.0062 | 54 (42) | 46 (53) | 8 (19) |  |
  ≥ 0.0062 | 75 (58) | 40 (47) | 35 (81) |  |