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Table 2 The pathways associated with surgery effects and recovery

From: Early changes in tear film protein profiles after femtosecond LASIK surgery

Categories

Diseases or Functions Annotation

Vpre vs Vpost

Vpost vs V1m

Z-score

Adj P

Protein count

Z-score

Adj P

Protein count

Organismal survival

Morbidity or mortality

− 4.3

0.007

41

3.5

0.021

29

Organismal death

− 4.2

0.009

40

3.3

0.028

28

Cell death and survival

Apoptosis

   

2.1

0.003

34

Protein synthesis

Quantity of enzyme

− 2.2

0.025

5

   

Tissue morphology

Quantity of leukocytes

− 2.4

0.005

21

   

Quantity of blood cells

− 2.1

0.007

22

   

Inflammatory response

Inflammation of organ

− 2.1

 < 0.001

38

   

Energy production

Concentration of ATP

2.1

0.039

5

   

Inflammatory response

Inflammatory response

2.3

0.006

19

   

Cellular movement

Chemotaxis

2.6

0.020

13

   

Chemotaxis of leukocytes

2.6

0.003

12

   

Chemotaxis of myeloid cells

2.6

0.005

10

   

Chemotaxis of neutrophils

2.2

0.022

6

   

Chemotaxis of phagocytes

2.6

0.006

10

   

Migration of cells

2.9

 < 0.001

71

− 2.6

 < 0.001

56

Leukocyte migration

2.3

 < 0.001

54

   

Cell movement

3.1

 < 0.001

79

− 3.0

 < 0.001

62

Cell movement of leukocytes

2.4

0.006

19

   

Cell movement of myeloid cells

2.5

0.007

15

   

Vascular system development and function

Angiogenesis

3.3

0.024

19

   

Development of vasculature

3.3

0.036

20

   

Infectious diseases

Viral Infection

3.6

 < 0.001

37

− 2.8

0.002

24

Replication of virus

3.2

0.003

15

− 2.6

0.010

11

Replication of RNA virus

2.9

0.007

13

− 2.2

0.028

9

Infection by RNA virus

   

-2.6

0.028

13

  1. Cancer-related terms are excluded from the table
  2. Vpre  preoperative visit, Vpost postoperative visit 1.5 h after surgery, V1m follow-up visit 1 month after surgery