Table 3 Student’s t-test analysis of tear proteome from patients diagnosed with pterygium versus control
Gene name | Protein | p-value | FDR 5% | FDR 1% | FWER | Control average LFQ log transformed | Pterygium average LFQ log transformed | SE of difference |
|---|---|---|---|---|---|---|---|---|
SERPINA1 | Alpha-1-antitrypsin; Short peptide from AAT | 2.55E−03 | N | N | N | 25.8 | 23.2 | 0.7 |
ORM1 | Alpha-1-acid glycoprotein 1 | 3.01E−03 | N | N | N | 26.0 | 23.2 | 0.7 |
APOA1 | Apolipoprotein A-I; Truncated apolipoprotein A-I | 5.11E−03 | N | N | N | 27.3 | 23.3 | 1.1 |
SERPINA3 | Alpha-1-antichymotrypsin | 1.69E−02 | N | N | N | 25.2 | 23.6 | 0.6 |
IGHG2 | Ig gamma-2 chain C region | 3.17E−02 | N | N | N | 26.5 | 24.4 | 0.8 |
CTSD | Cathepsin D | 4.27E−02 | N | N | N | 24.4 | 22.8 | 0.7 |
SERPINC1 | Antithrombin-III | 4.52E−02 | N | N | N | 25.9 | 24.0 | 0.8 |
PIP | Prolactin-inducible protein | 4.90E−02 | N | N | N | 31.6 | 29.0 | 1.2 |
A1BG | Alpha-1B-glycoprotein | 4.92E−02 | N | N | N | 23.4 | 21.9 | 0.6 |