Table 2 Correlations of HMGB2 expression with clinicopathological parameters in primary cervical cancer tissues
Variables | No. of cases | HMGB2 expression | P value | |
|---|---|---|---|---|
Low | High | |||
Age (year) | ||||
  < 50 | 15 | 4 | 11 | 0.273 |
  ≥ 50 | 14 | 5 | 9 | |
Family history of malignant tumors | ||||
 Yes | 3 | 1 | 2 | 0.460 |
 No | 26 | 8 | 18 | |
P16 expression | ||||
 Positive | 29 | 9 | 20 |  |
 Negative | 0 | 0 | 0 | |
Primary tumor size(cm) | ||||
 < 3 | 7 | 5 | 2 | 0.015* |
  ≥ 3 | 22 | 4 | 18 | |
Pelvic lymph node metastasis | ||||
 Positive | 8 | 2 | 6 | 0.325 |
 Negative | 21 | 7 | 14 | |
Infiltration depth | ||||
 Superficial/Deep fibrous histiocytoma | 18 | 8 | 10 | 0.048* |
 Outer layer of the cervix | 11 | 1 | 10 | |
The FIGO stage | ||||
 Ia-Ib1 | 15 | 8 | 7 | 0.009* |
 Ib2-IIa2 | 14 | 1 | 13 | |