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Table 2 Correlations of HMGB2 expression with clinicopathological parameters in primary cervical cancer tissues

From: Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer

Variables No. of cases HMGB2 expression P value
Low High
Age (year)
  < 50 15 4 11 0.273
  ≥ 50 14 5 9
Family history of malignant tumors
 Yes 3 1 2 0.460
 No 26 8 18
P16 expression
 Positive 29 9 20  
 Negative 0 0 0
Primary tumor size(cm)
 < 3 7 5 2 0.015*
  ≥ 3 22 4 18
Pelvic lymph node metastasis
 Positive 8 2 6 0.325
 Negative 21 7 14
Infiltration depth
 Superficial/Deep fibrous histiocytoma 18 8 10 0.048*
 Outer layer of the cervix 11 1 10
The FIGO stage
 Ia-Ib1 15 8 7 0.009*
 Ib2-IIa2 14 1 13
  1. *P < 0.05
  2. FIGO International Federation of Gynecology and Obstetrics
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