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Table 2 IgG glycome composition in gastric cancer patients with or without response to NACT

From: Prediction of neoadjuvant chemotherapeutic efficacy in patients with locally advanced gastric cancer by serum IgG glycomics profiling

IgG glycomeTraits (composition)Mean NRGa)Mean (RGa)P valueAUCConfidence interval (95%)
Directly detected glycansGP1 (H3N3F1)0.1370.1820.0480.6780.524–0.832
GP2 (H3N4)0.6230.8280.0750.6580.501–0.816
GP3 (H3N5)0.0130.0050.1790.5680.406–0.730
GP4 (H3N4F1)22.58027.4480.0030.7710.628–0.913
GP5 (H5N2)0.1570.1440.4600.4740.309–0.639
GP6 (H3N5F1)6.5887.5770.0420.6540.498–0.811
GP7 (H4N4)0.3530.3480.9020.5190.352–0.687
GP8 (H4N4F1(6))20.34419.6280.2640.6220.462–0.783
GP9 (H4N4F1(3))10.1089.9250.6780.5410.372–0.709
GP10 (H4N5F1(6))6.4246.0970.4460.4620.296–0.629
GP11 (H4N5F1(3))0.6910.7250.5420.4510.286–0.616
GP12 (H5N4)1.0050.8200.2760.5390.374–0.705
GP13 (H5N5)0.0330.0140.2090.5680.406–0.731
GP14 (H5N4F1)15.78312.9440.0070.7900.650–0.930
GP15 (H5N5F1)1.8401.4960.0170.7120.559–0.865
GP16 (H4N4F1S1(3))2.3132.2550.6570.5680.404–0.733
GP17 (H5N4S1)0.6200.5210.1460.5770.413–0.741
GP18 (H5N4F1S1)7.2185.9760.0280.7100.559–0.861
GP19 (H5N5F1S1)0.7780.7370.4460.5890.424–0.755
GP20 (H5N4F2S1)0.0270.0110.1680.5710.409–0.733
GP21 (H5N4S2)0.4950.5190.6920.5280.361–0.696
GP22 (H5N5S2)0.0030.0020.6220.5550.392–0.718
GP23 (H5N4F1S2)0.8350.7920.6890.5820.414–0.750
GP24 (H5N5F1S2)1.0331.0060.8590.4840.317–0.651
Main summarized traitsGPN86.68288.1820.0590.6420.482–0.802
S1 total10.9299.4890.0290.6950.543–0.847
S2 total2.3642.3180.8710.5280.360–0.695
S total13.29211.8080.0610.6420.482–0.802
G0 total29.94136.0400.0020.7730.630–0.917
G1 total37.92036.7240.0640.6850.531–0.839
G2 total18.66315.2730.0060.7980.658–0.939
F total94.57294.7980.5050.4870.319–0.654
F neutral97.47397.5560.7970.5340.365–0.703
F sialo91.66990.9410.1850.6230.463–0.783
B total17.40217.6600.7700.5310.365–0.697
B neutral17.99818.0070.9930.5100.343–0.677
B sialo13.65014.6610.4130.5650.400–0.730
Gal-ratio0.3700.526< 0.0010.7760.633–0.919
FG00.2380.2900.0020.7680.625–0.911
FG10.3220.3110.1210.6330.477–0.790
FG20.1680.1360.0060.7860.647–0.925
  1. aRG, patients with response to NACT; NRG, patients without response to NACT; H, Mannose; N, N-acetylglucosamine; F, Fucose; S, N-acetylneuraminic acid; italic font indicates the trait exist significant difference