Fig. 3
From: Rational selection of a biomarker panel targeting unmet clinical needs in kidney injury
Desirable time kinetics of kidney injury biomarkers. The four unmet clinical needs in kidney injury all require specific biomarker rise and fall patterns. For early diagnosis, early rises within hours are essential whereas for late diagnosis a protracted time kinetic is needed. For risk stratification the biomarker concentration should be altered prior to the intervention. For kidney injury monitoring, a close relation to structural damage is needed