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Fig. 3 | Clinical Proteomics

Fig. 3

From: O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature

Fig. 3

The inhibition of OGA activity alters the molecular signature of GBM secretome. a Venn diagram showing the distribution of proteins identified in the label free proteomic quantifications between control and iOGA groups. b PANTHER GO molecular function classification of the proteins identified and previously distributed between the control (blue) and iOGA (red) groups. c Volcano plot showing the 51 proteins whose abundance has changed significantly upon iOGA treatment. p < 0.05 (d) Heat map grouping the 51 proteins with altered abundance according to up regulation (red) or down regulation (blue) between control and iOGA groups. e String illustrating the interactions detected between proteins that belong to CCKR signaling pathway and (f) Inflammation mediated by chemokine and cytokine signaling pathway

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Clinical Proteomics

ISSN: 1559-0275