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Fig. 3 | Clinical Proteomics

Fig. 3

From: A rigorous evaluation of optimal peptide targets for MS-based clinical diagnostics of Coronavirus Disease 2019 (COVID-19)

Fig. 3

Protein assignment of detected and validated SARS-CoV-2 peptides: Circos plot of peptides against SARS-CoV-2 proteins (outermost ring). Of the 639-peptide panel (2nd outermost ring), many peptides could be identified using our validation workflow in clinical and cell culture datasets (3rd outermost ring). Peptides derived from ORF9b, papain-like protease, Nsp4, Nsp10, uridylate endoribonuclease (Nsp15) and certain spike protein peptides were only found in cell culture datasets (2nd innermost ring). Final peptides chosen for targeted analysis are annotated in the innermost ring. Circos plot was generated in Galaxy [65]

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Clinical Proteomics

ISSN: 1559-0275