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Fig. 3 | Clinical Proteomics

Fig. 3

From: Quantitative proteomics reveals the effect of Yigu decoction (YGD) on protein expression in bone tissue

Fig. 3

TMT quantitative proteomic analysis of differentially expressed proteins after YGD treatment. a The volcano plot was drawn using two factors, log2 fold change (log2FC) and P value (Logarithmic transformation based on 10, Student's t-test). The significantly downregulated proteins are annotated in blue (FC < 0.833 and P < 0.05), the significantly upregulated proteins are annotated in red (FC > 1.2 and P < 0.05), and the proteins without differences are indicated in gray. b The hierarchical clustering results are presented as a tree-type heatmap with the abscissa showing the sample information and the ordinate showing the significantly differentially expressed proteins, and the expression amounts of the significantly different proteins in different samples were exhibited in the Heatmap by different colors after normalization using the log2 method. Where red represents the significantly upregulated proteins, blue represents the significantly downregulated proteins and grey represents proteins with no quantitative information

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