Analytical validation of a multi-biomarker algorithmic test for prediction of progressive kidney function decline in patients with early-stage kidney disease

Table 7 KidneyIntelX risk score reproducibility results for ten patient samples across 20 replicates

Sample	N	Mean predicted probabilities	SD	%CV
Low risk^a
Sample 1	20	0.138	0.002	1.4
Intermediate risk^a
Sample 2	20	0.215	0.022	10.4
Sample 3	20	0.178	0.012	7.0
Sample 4	20	0.209	0.001	0.3
Sample 5	20	0.169	0.008	4.7
Sample 6	20	0.164	0.001	0.8
Sample 7	20	0.197	0.013	6.6
High risk^a
Sample 8	20	0.424	0.026	6.2
Sample 9	20	0.366	0.016	4.3
Sample10	20	0.295	0.014	4.8

^aKidneyIntelX risk categories are based on previously validated cut-offs and represent scaled KidneyIntelX risk scores ≤ 45 for low risk, ≥ 50 and ≤ 85 for intermediate risk, and > 85 for high risk. Predicted probabilities are scaled to align with a continuous risk score from 5 to 100 by increments of 5

ISSN: 1559-0275