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Fig. 2 | Clinical Proteomics

Fig. 2

From: Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis

Fig. 2

The most-significant proteins in the placenta accreta group. a Plot showing expression of transcripts, red triangles denote up-regulated genes, blue squares denote down-regulated genes, and grey dots denote non-regulated genes; b volcano plot of proteins, red dots denote up-regulated proteins, green dots denote down-regulated proteins, and grey dots denote non-regulated proteins, transverse dashed line denotes “−log10(0.05)”, vertical dashed line denotes “log2(0.67)” and “log2(1.5)” (from left to right); c 2D plot of the correlation between the DEGs and DEPs which showed the correlation coefficient was 0.14 (dashed line), the x-axis is the protein expression level, and the y-axis is the gene expression level; d Venn diagram to reflect the 0.09% overlap degree and 33 overlapping genes between the transcripts and proteins. Heatmaps of 37,743 transcripts (e) and 160 proteins (f), and heatmaps of 33 overlapping transcripts (g) and 33 proteins (h). FC: fold change; DEGs: differentially expressed genes; DEPs: differentially expressed proteins; PA: placenta accreta

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