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Fig. 5 | Clinical Proteomics

Fig. 5

From: Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis

Fig. 5

MeCP2, PODN and ApoD downregulation promotes the migration and invasion of HTR-8/SVneo cells. a, b Levels of MeCP2, PODN and ApoD proteins detected after transfection of HTR-8/SVneo cells with siRNA for MeCP2, PODN and ApoD, respectively. c MeCP2, PODN and ApoD mRNA expression examined after 48-h transfection. d, e Transwell migration and invasion assays showing higher numbers of migrated and invaded cells in the si-MeCP2, si-PODN and si-ApoD group than in the NC group (×200). All data are presented as the mean ± standard deviation. NC: negative control; MeCP2: Methyl-CpG-binding domain protein 2; ApoD: Apolipoprotein D; PODN: Podocan. *P < 0.05

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Clinical Proteomics

ISSN: 1559-0275