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Table 1 Baseline characteristics of included study participants. Data presented as median (IQR) or percentange (%). P-values obtained using the Mann-Whitney U test.

From: Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases

Characteristics

Cases (n = 215)*

Controls (n = 230)*

p-value

Age (years)

28 (16–41)

29 (23–41)

0.014

Gender, Male n (%)

63 (29.3%)

75 (32.6%)

0.45

BMI (kg/m2)

20.6 (16.3–24.7)

23.8 (20.8–29.2)

6.02e-12

BMI in participants ≥ 18yrs

23.0 (19.8–25.9)

23.9 (20.9–29.6)

0.005

NYHA Index

I = 4; II = 150

III = 36; IV = 10

N/A

N/A

Number of participants taking penicillin prophylaxis

111

0

N/A

Number of participants taking anticoagulation

23

0

N/A

  1. *15 cases and 8 controls have BMI data missing. Missing data are removed from the statistical computation