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Fig. 4 | Clinical Proteomics

Fig. 4

From: Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework

Fig. 4

Classification results muscle-infiltrating vs. non-muscle infiltrating tumors and visualizations of their top m/z features. a Classification included feature selection based on t-statistics values above zero reveals 35 muscle-infiltrating specific and 36 non-muscle infiltrating specific m/z features. b Average mass spectra plots for the top m/z feature per group on binned, filtered, combined and smoothed MSI data. c Ion images of the top m/z feature per group were plotted on five tissue cores with contrast enhancement ‘histogram’ on binned, filtered, combined and TIC normalized data

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