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Fig. 8 | Clinical Proteomics

Fig. 8

From: Serum proteomics unveil characteristic protein diagnostic biomarkers and signaling pathways in patients with esophageal squamous cell carcinoma

Fig. 8

Validation of ESCC-related candidate biomarker panel. A–F Representative images of carcinoma tissue and their ANT stained for ENO1, TPI1, PGAM1, SAA1 and S100A8/A9 (brown) using immunohistochemistry assay (×100), respectively. a NAT and b CT. G Scores from staining intensity and numbers in 29 pairs of brown cells in cancer and adjacent normal tissues. H–L Quantification analysis of S100A8/A9, SAA1, ENO1, TPI1 and PGAM1 in serum from healthy controls and ESCC patients. M ROC curve for serum against SAA1, S100A8/A9, ENO1, TPI1, PGAM1 and their combination for patients with ESCC versus normal controls. ANT adjacent normal tissue, CT carcinoma tissue

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Clinical Proteomics

ISSN: 1559-0275