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Fig. 4 | Clinical Proteomics

Fig. 4

From: Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics

Fig. 4

Automated plasma proteome profiling procedure of colon cancer patients. A Overview of the identified protein groups and peptides in each individual sample. B Percentage of detected proteins in all the 30 samples, in 25–29, in 16–24, in 2–15 samples. C Top 20 of Gene Ontology enrichments for cellular component. D sPLS-DA scores plots based on the colon cancer patients’ dataset (Red, patients aged 30–49; Green, patients aged 50–69; Blue, patients aged 70 +). E Volcano plot of statistical significance against log2-fold change between age 30–49 (n = 10) and age 70 + (n = 10) in colon cancer cohort. Significance is controlled by p-value (independent two-sample t-test, two-sided) and minimum fold change (s0 parameter in Perseus) indicated by the cutoff curve

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