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Table 2 The biological processes enriched by differential expressed proteins

From: The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study

GO_ID

Term

Differential expressed proteins

P value

GO:0006953

Acute-phase response

ITIH4, SERPINA3, HP, LBP, SERPINF2, CRP, CD163, ORM1, ORM2

 < 0.001

GO:0034121

Regulation of toll-like receptor signaling pathway

CD14, LBP, RSAD2, PTPRS

0.005

GO:0002526

Acute inflammatory response

C3, ICAM1, KLKB1, ITIH4, SERPINA3, HP, LBP, SERPINF2, CRP, CD163, ORM1, ORM2, CFB, C1R, C2, C9, C1S, C8A, CPN2, CFHR5, IGKV4-1, IGHV1-46, VCAM1

0.005

GO:0002366

Leukocyte activation involved in immune response

LBP, ORM1, LCN2, CTSD, PYGB, KPNB1, LYZ, ORM2, ARPC5, CAPN1, CAB39, EEF2, DEFA1, PSAP, CAMP, OSTF1, ACLY, ANPEP, SLPI, CORO1A, SEMA4A, TGFB1

0.007

GO:0002263

Cell activation involved in immune response

GRN, LBP, ICAM1, FGL2, C3, SERPINA3, HP, A1BG, CAT, LRG1, CD14, GGH, ORM1, LCN2, CTSD, PYGB, KPNB1, LYZ, ORM2, ARPC5, CAPN1, CAB39, EEF2, DEFA1, PSAP, CAMP, OSTF1, ACLY, ANPEP, SLPI, CORO1A, SEMA4A, TGFB1, FMOD, SELL

0.009

GO:0007179

Transforming growth factor β (TGFβ) receptor signaling pathway

FMOD, TGFB1, LRG1, VASN, COL3A1, CDH5

0.044