Table 2 Top 30 up-regulated DEPs
From: Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets
Accessions ID | Genes | Protein descriptions(Full name) | PG.Protein names | log2_FC_median (log ratio) | FC_median (ratio) | Pvalue | Ajusted pvalue | median_normal | median_SCCC | Avg (Normal) | Avg (SCCC) | Std (Normal) | Std (Normal) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Q9UEW8 | STK39 | STE20/SPS1-related proline-alanine-rich protein kinase | STK39_HUMAN | 7.36119336 | 164.4144581 | 0.018860878 | 0.101659984 | 211.4552765 | 34,766.30469 | 1527.338822 | 49,956.00369 | 2848.88591 | 44,771.05061 |
Q9Y3R5 | DOP1B | Protein dopey-2 | DOP2_HUMAN | 7.047271208 | 132.2635031 | 0.009017667 | 0.067617556 | 390.7667237 | 51,684.17579 | 455.894511 | 53,527.82245 | 145.6301596 | 43,456.97949 |
Q9UBW7 | ZMYM2 | Zinc finger MYM-type protein 2 | ZMYM2_HUMAN | 6.288898031 | 78.18923194 | 0.004630235 | 0.050678673 | 529.169983 | 41,375.39454 | 4620.847708 | 40,939.30145 | 9149.269534 | 26,504.5089 |
P12532 | CKMT1A | Creatine kinase U-type, mitochondrial | KCRU_HUMAN | 5.738345477 | 53.38436902 | 0.001805234 | 0.030247698 | 16,038.71924 | 856,216.9063 | 25,622.14437 | 917,631.895 | 18,427.92428 | 589,576.229 |
P42771 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | CDN2A_HUMAN | 5.498126381 | 45.19609998 | 0.000982386 | 0.021234095 | 4311.488404 | 194,862.461 | 7345.865885 | 220,803.6349 | 8252.474718 | 131,670.3183 |
O75146 | HIP1R | Huntingtin-interacting protein 1-related protein | HIP1R_HUMAN | 5.44650024 | 43.60737491 | 0.042449977 | 0.159768091 | 556.9887085 | 24,288.81543 | 4073.540395 | 23,434.23526 | 7863.248618 | 20,583.82942 |
Q9BVW5 | TIPIN | TIMELESS-interacting protein | TIPIN_HUMAN | 5.420841786 | 42.83867003 | 0.024706829 | 0.120254705 | 1097.918701 | 47,033.37696 | 1097.918701 | 53,906.45801 | 2.27E-13 | 51,368.51886 |
Q9H6K5 | PRR36 | Proline-rich protein 36 | PRR36_HUMAN | 5.277000873 | 38.77354861 | 0.010817348 | 0.075164197 | 1270.526734 | 49,262.83008 | 1482.28119 | 44,692.1954 | 473.497357 | 36,396.36268 |
Q96GM5 | SMARCD1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | SMRD1_HUMAN | 5.204188829 | 36.86522939 | 0.008387325 | 0.065647507 | 1221.024536 | 45,013.34961 | 6056.397216 | 53,136.54706 | 7348.723373 | 37,892.81275 |
P11388 | TOP2A | DNA topoisomerase 2-alpha | TOP2A_HUMAN | 5.115361941 | 34.66389679 | 0.023438944 | 0.116781697 | 1477.363159 | 51,211.16407 | 1946.478332 | 83,853.67923 | 1048.973417 | 78,872.81998 |
Q460N5 | PARP14 | Protein mono-ADP-ribosyltransferase PARP14 | PAR14_HUMAN | 5.051141315 | 33.15469584 | 0.044442 | 0.163637227 | 9322.803161 | 309,094.7032 | 113,391.6547 | 370,861.0882 | 178,506.0581 | 263,836.9669 |
Q8NFP9 | NBEA | Neurobeachin | NBEA_HUMAN | 4.967745586 | 31.29251235 | 0.028754464 | 0.130171978 | 1074.147766 | 33,612.78223 | 5972.771382 | 43,643.51539 | 7428.877063 | 37,508.36122 |
P12314 | FCGR1A | High affinity immunoglobulin gamma Fc receptor I | FCGR1_HUMAN | 4.913751049 | 30.14299885 | 0.005041107 | 0.052147793 | 2469.903321 | 74,450.29297 | 2881.553874 | 99,400.99513 | 920.4786202 | 72,657.58303 |
P52756 | RBM5 | RNA-binding protein 5 | RBM5_HUMAN | 4.878839207 | 29.42232208 | 0.011560853 | 0.077216487 | 2238.103272 | 65,850.19532 | 19,502.76416 | 67,707.54153 | 25,939.69471 | 38,207.43809 |
P0DN79 | CBSL | Cystathionine beta-synthase-like protein;Cystathionine beta-synthase | CBSL_HUMAN;CBS_HUMAN | 4.814433533 | 28.13772013 | 0.044546292 | 0.163843433 | 2436.617432 | 68,560.85938 | 2842.720337 | 88,476.12218 | 908.0737018 | 94,257.57237 |
P18858 | LIG1 | DNA ligase 1 | DNLI1_HUMAN | 4.761255341 | 27.11943732 | 0.004953393 | 0.051713424 | 4643.395508 | 125,926.2735 | 6351.933756 | 133,251.627 | 2432.224844 | 95,289.99818 |
P40938 | RFC3 | Replication factor C subunit 3 | RFC3_HUMAN | 4.751387685 | 26.9345804 | 0.002498748 | 0.036112277 | 1982.11731 | 53,387.49805 | 12,027.9799 | 66,241.66961 | 14,209.03093 | 36,349.16249 |
Q96S86 | HAPLN3 | Hyaluronan and proteoglycan link protein 3 | HPLN3_HUMAN | 4.687638778 | 25.77032414 | 0.049269072 | 0.1739184 | 3618.05542 | 93,238.46093 | 13,298.16699 | 153,378.2993 | 20,717.3008 | 157,400.3024 |
O14683 | TP53I11 | Tumor protein p53-inducible protein 11 | P5I11_HUMAN | 4.686881021 | 25.75679216 | 0.017581321 | 0.097509494 | 1945.32251 | 50,105.26758 | 2269.542928 | 62,968.96597 | 724.9788951 | 55,452.83062 |
Q6NXG1 | ESRP1 | Epithelial splicing regulatory protein 1 | ESRP1_HUMAN | 4.632471609 | 24.80349659 | 0.010347592 | 0.07323217 | 2582.032471 | 64,043.4336 | 17,814.92733 | 63,677.24805 | 22,823.02529 | 36,027.97701 |
P09326 | CD48 | CD48 antigen | CD48_HUMAN | 4.608239287 | 24.39036236 | 0.027588616 | 0.126754466 | 1614.560547 | 39,379.7168 | 4874.363201 | 52,028.30914 | 5500.379072 | 46,760.21024 |
Q16576 | RBBP7 | Histone-binding protein RBBP7 | RBBP7_HUMAN | 4.58773499 | 24.04616619 | 0.032354519 | 0.13858515 | 2554.079346 | 61,415.81641 | 7752.206951 | 68,417.96881 | 10,522.55828 | 61,982.56732 |
Q8NBJ4 | GOLM1 | Golgi membrane protein 1 | GOLM1_HUMAN | 4.575636972 | 23.84536517 | 0.010995783 | 0.075431856 | 2863.917237 | 68,291.15235 | 17,917.06983 | 69,412.97833 | 21,812.35588 | 41,626.55051 |
Q99436 | PSMB7 | Proteasome subunit beta type-7 | PSB7_HUMAN | 4.551344635 | 23.44721447 | 0.013162013 | 0.083884171 | 9781.66699 | 229,352.8438 | 43,456.63834 | 255,166.8022 | 71,014.90995 | 179,459.6422 |
Q9NVP2 | ASF1B | Histone chaperone ASF1B | ASF1B_HUMAN | 4.550893393 | 23.43988185 | 0.004111323 | 0.046576686 | 4228.997559 | 99,127.20313 | 4228.997559 | 117,532.7544 | 0 | 82,982.34381 |
Q9H5H4 | ZNF768 | Zinc finger protein 768 | ZN768_HUMAN | 4.421533747 | 21.42961086 | 0.007044493 | 0.060974403 | 1769.069214 | 37,910.46485 | 1769.069214 | 33,820.35429 | 2.27E-13 | 25,296.06673 |
Q9NX00 | TMEM160 | Transmembrane protein 160 | TM160_HUMAN | 4.409021661 | 21.2445615 | 0.04356989 | 0.16138934 | 88,124.80078 | 1,872,172.75 | 649,803.9105 | 1,881,539.407 | 844,979.995 | 1,257,655.391 |
Q9Y6V7 | DDX49 | Probable ATP-dependent RNA helicase DDX49 | DDX49_HUMAN | 4.378939624 | 20.8061716 | 0.012018926 | 0.079416196 | 491.5249024 | 10,226.75146 | 491.5249024 | 11,117.62381 | 0 | 9103.12609 |
O60725 | ICMT | Protein-S-isoprenylcysteine O-methyltransferase | ICMT_HUMAN | 4.319314494 | 19.9638006 | 0.043375703 | 0.161197986 | 2481.373047 | 49,537.63672 | 2894.935222 | 66,127.60634 | 924.7531351 | 69,178.19749 |
Q96P11 | NSUN5 | Probable 28S rRNA (cytosine-C(5))-methyltransferase | NSUN5_HUMAN | 4.265183131 | 19.22861745 | 0.006070132 | 0.057450371 | 1004.54303 | 19,315.97364 | 2422.19635 | 21,998.87501 | 2745.33897 | 15,040.52151 |