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Table 4 List of complements and complement-regulating proteins

From: Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis

Accession ID

NCBInr DB

Accession ID

GenBank DB

Protein name

Sequence

coverage

(%)

Peptide

Match

(n)

IgAN-I (n = 6) /

Control (n = 5) ratio

(Ratio variability [%])

IgAN-II (n = 6) /

Control (n = 5) ratio

(Ratio variability [%])

IgAVN-I (n = 6) /

Control (n = 5) ratio

(Ratio variability [%])

IgAVN-II (n = 6) /

Control (n = 5) ratio

(Ratio variability [%])

115298678

 

C3

17

25

6.75 * (114.91)

5.35 * (107.18)

4.86 (93.25)

2.64 (92.76)

443671

 

C4A

 4

 4

4.51 (65.96)

4.72 (89.78)

3.12 (61.45)

4.00 (72.75)

953514538

 

C5

 2

 2

100 **

100 **

100 **

100 **

109731764

 

C8γ

13

 2

2.00 (46.48)

2.19 (46.82)

0.65 (3.71)

1.08 (16.90)

119576392

 

C9

14

 8

16.72 ** (98.31)

9.78 ** (113.13)

7.45 * (89.20)

4.24 (88.87)

183763

 

CFHR1

32

 8

9.66 * (78.53)

5.58 * (111.92)

3.00 (107.85)

3.25 (84.79)

767910533

 

CFHR5

 4

 2

100 **

100 **

100 **

100 **

13477169

 

Vitronectin

15

 7

3.82 (102.41)

3.75 (110.86)

2.84 (105.66)

3.03 (109.83)

578815184

 

Clusterin

20

13

2.48 (87.08)

2.41 (109.01)

1.81 (84.97)

1.57 (77.56)

4502503

 

C4BPA

 4

 2

1.71 (113.99)

1.89 (83.17)

0.80 (57.79)

0.63 (75.75)

809019

X05309.1

CR1

 3

 3

0.53 (115.68)

0.27 (123.83)

0.57 (86.45)

0.50 (106.89)

  1. C4BPA: C4b-binding protein α chain; CFHR: complement factor H-related protein; CR1: complement receptor 1; DB: database; IgAN: IgA nephropathy; IgAVN: IgA vasculitis with nephritis; NCBInr: National Center for Biotechnology information non-redundant
  2. *P < 0.05, **P < 0.01