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Table 3 Summary of ELISA results indicated as median (25%, 75% quartile)

From: Identification and Validation of Proteinase 3 and Latent Matrix-Metalloproteinase 9 as Potential Biomarkers for Chronic Lung Transplant Rejection

 

Number of samples

IgM (ug/mg)

Lysozyme (ug/mg)

PR-3 (ng/mg)

proMMP-9 (ng/mg)

aMMP-9 (ng/mg)

aMMP-9 (ng/ml)

Control

48

0.96 (0.37, 1.85)

6.32 (3.55, 12.1)

152 (65, 246)

12.7 (4.68, 64.7)

11.1 (3.45, 33.2)

0.53 (0.18, 1.21)

PreBOS16–76

27

0.75 (0.35, 1.54)

3.47 (1.74, 8.73)

36 (15, 243)

19.6 (2.31, 58.2)

19.3 (8.83, 38.0)

0.97 (0.17, 1.71)

PreBOS1–15

32

1.31 (0.41, 3.44)

4.88 (2.68, 8.98)

247 (33, 1,543)

112 (13.2, 508)***

9.33 (3.09, 26.8)

1.83 (0.53, 2.99)**

BOS

17

2.35 (0.59, 5.18)**

6.47 (3.20, 11.2)

1,337 (735, 4,106)*

837 (279, 3058)*

20.2 (9.09, 23.8)

2.25 (0.79, 3.16)**

  1. Significance test between BOS and control group.
  2. *p < 0.0001
  3. **p < 0.01
  4. ***p < 0.05