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Research
Non-small cell lung carcinoma (NSCLC) remains the leading cause of cancer deaths in the United States. More than half of NSCLC patients have clinical presentations with locally advanced or metastatic disease a...
Clinical Proteomics 2017 14:31
Published on: 15 August 2017
Research
The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with pro...
Clinical Proteomics 2017 14:30
Published on: 14 August 2017
Research
Hepatocellular carcinoma is an aggressive malignancy with poor prognosis and easy to recur even the tumor is totally removed by surgery. Portal vascular invasion is one of the major factors contributing to tum...
Clinical Proteomics 2017 14:29
Published on: 2 August 2017
Research
The aim was to improve upon an existing blood-based colorectal cancer (CRC) test directed to high-risk symptomatic patients, by developing a new CRC classifier to be used with a new test embodiment. The new te...
Clinical Proteomics 2017 14:28
Published on: 25 July 2017
Research
Post-stroke infections occur in 20–36% of stroke patients and are associated with high morbidity and mortality rates. Early identification of patients at risk of developing an infection could improve care via ...
Clinical Proteomics 2017 14:27
Published on: 12 July 2017
Research
Mesenchymal stem/stromal cells (MSC) display a range of immunoregulatory properties which can be enhanced by the exposure to cytokines such interferon γ (IFN-γ). However the compositional changes associated wi...
Clinical Proteomics 2017 14:26
Published on: 6 July 2017
Research
The number of pulmonary nodules detected in the US is expected to increase substantially following recent recommendations for nationwide CT-based lung cancer screening. Given the low specificity of CT screenin...
Clinical Proteomics 2017 14:25
Published on: 5 July 2017
Review
Growth hormone (GH) is a protein that is known to stimulate postnatal growth, counter regulate insulin’s action and induce expression of insulin-like growth factor-1. GH exerts anabolic or catabolic effects de...
Clinical Proteomics 2017 14:24
Published on: 29 June 2017
Research
The pathogenesis of systemic lupus erythematosus (SLE) is poorly understood but has been linked to defective clearance of subcellular particulate material from the circulation. This study investigates the orig...
Clinical Proteomics 2017 14:23
Published on: 21 June 2017
Research
Atherosclerotic plaque rupture is the culprit event which underpins most acute vascular syndromes such as acute myocardial infarction. Novel biomarkers of plaque rupture could improve biological understanding...
Clinical Proteomics 2017 14:22
Published on: 19 June 2017
Research
Mycobacterium tuberculosis (Mtb) is the causative agent of Tuberculosis (TB), the number one cause of death due to an infectious disease. TB diagnosis is performed by microscopy, cultu...
Clinical Proteomics 2017 14:21
Published on: 5 June 2017
Research
Ovarian cancer is one of the most lethal gynecological malignancies, in which platinum resistance is a common cause of its relapse and death. Glycosylation has been reported to be involved in drug resistance, ...
Clinical Proteomics 2017 14:20
Published on: 23 May 2017
Research
The Xiaoke Pill containing Chinese herb extracts and Glibenclamide, is used in therapy for type 2 diabetes mellitus (T2DM), and is effective in reducing the risk of hypoglycemia and improving diabetes symptoms...
Clinical Proteomics 2017 14:19
Published on: 17 May 2017
Research
To develop a new molecular targeted treatment for brain (AVMs), identification of membrane proteins that are localised on the AVM endothelium is crucial. Current treatment methods are surgery and radiosurgery....
Clinical Proteomics 2017 14:17
Published on: 16 May 2017
Research
Nephrotic syndrome (NS) is a nonspecific kidney disorder, commonly caused by minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and membranous nephropathy (MN). Here we analyzed urinary p...
Clinical Proteomics 2017 14:18
Published on: 16 May 2017
Research
Epithelial ovarian carcinomas encompass a heterogeneous group of diseases with a poor 5-year survival rate. Serous carcinoma is the most common type. Most FDA-approved serum tumor markers are glycoproteins. Th...
Clinical Proteomics 2017 14:16
Published on: 10 May 2017
Research
Aberrant expression of Na+/K+-ATPase α1 subunit (ATP1A1) is widely observed in multiple types of tumors, and its tissue-specific expression relates to cancer development. However, the functions and molecular mech...
Clinical Proteomics 2017 14:15
Published on: 4 May 2017
Research
The systematic mechanisms of acute intracerebral hemorrhage are still unknown and unverified, although many recent researches have indicated the secondary insults. This study was aimed to disclose the patholog...
Clinical Proteomics 2017 14:14
Published on: 26 April 2017
Research
X-linked retinoschisis (XLRS) is a vitreoretinal degenerative disorder causing vision deterioration, due to structural defects in retina. The hallmark of this disease includes radial streaks arising from the f...
Clinical Proteomics 2017 14:13
Published on: 24 April 2017
Research
Calcific aortic stenosis (CAS) is the most common heart valve disease in the elderly, representing an important economic and social burden in developed countries. Currently, there is no way to predict either t...
Clinical Proteomics 2017 14:12
Published on: 21 April 2017
Review
Subcellular microvesicles (MVs) have attracted increasing interest during the past decades. While initially considered as inert cellular debris, several important roles for MVs in physiological homeostasis, ca...
Clinical Proteomics 2017 14:11
Published on: 8 April 2017
Research
Recent epidemiological studies indicate that only 30–50% of undiagnosed type 2 diabetes mellitus (T2DM) patients are identified using glycated hemoglobin (HbA1c) and elevated fasting plasma glucose (FPG) levels. ...
Clinical Proteomics 2017 14:10
Published on: 28 March 2017
Research
Despite recent advances in colorectal cancer (CRC) diagnosis and population screening programs, the identification of patients with preneoplastic lesions or with early CRC stages remains challenging and is imp...
Clinical Proteomics 2017 14:9
Published on: 24 March 2017
Research
Tubulointerstitial nephritis antigen-like 1 protein (TINAGL1), is a matricellular protein, known to play role in cell adhesion and cell receptor interaction. Research related to TINAGL1 is limited to cell cult...
Clinical Proteomics 2017 14:8
Published on: 21 March 2017
Research
Endometriosis is a chronic gynecological inflammatory disease characterized by the presence of functional endometrial glands and stroma outside of the uterine cavity. It affects 7–10% of women of reproductive ...
Clinical Proteomics 2017 14:7
Published on: 2 February 2017
Clinical Proteomics is affiliated with the Human Proteome Organization (HUPO). HUPO is an international scientific organization representing and promoting proteomics through international cooperation and collaborations by fostering the development of new technologies, techniques and training.
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