Fig. 2

2-D gel images of MARS-treated plasma from both the control and the cancer samples separated on pH 4–7 strips and then resolved on 10% gels. Protein load was 40 μg for depleted plasma and 25 μg for both neat and HAP. a Representative protein profile from a neat plasma sample. b Representative protein profile from a depleted control sample. Proteins that are down-regulated are depicted in yellow. c Representative protein profile from a depleted cancer sample. Proteins that are up-regulated are depicted in red. d Representative protein profile from a depleted plasma sample depicting the HAP fraction only. e Representative protein profile from a depleted benign ovarian neoplasm sample. Proteins that are down-regulated are depicted in yellow; proteins that are up-regulated are depicted in red