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Table 1 Performance comparison of Scorr and Tcorr as determined by ROC area under various sizes of candidate peptide pool

From: Critical Evaluation of Product Ion Selection and Spectral Correlation Analysis for Biomarker Screening Using Targeted Peptide Multiple Reaction Monitoring

Size of candidate peptide pool

ROC area

T corr

S corr

10

0.937

0.939

100

0.916

0.910

1,000

0.907

0.871

  1. The entire set of putative b and y ions from DIMS library spectra were used for the Tcorr calculations
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Clinical Proteomics

ISSN: 1559-0275