Fig. 2

Data processing pipeline for peptidomic analysis using LC MALDI. Data processing involved transformation of large volume of raw into a list of nonredundant cross-category m/z features keeping track of sample source, retention time, and intensity. MASS-Conductor is an integrated suite of algorithms, statistical methods, and computer applications that interface with Applied Biosystems (Foster City, CA, USA), ThermoElectron (Waltham, MA, USA), and Agillent Biotechnologies (Palo Alto, CA, USA) instrument databases and discover discrimative peptide features and perform sample classification from protein mass spectrometry data