Table 2 List of peptides and their relative abundance in terms of fold change in AR urine when compared to STA urine with the ID of peptides that are sequenced
m/z(Da) | Fold change | Swiss Prot ID | Gene | Parent protein | Peptide sequence | |
|---|---|---|---|---|---|---|
High-abundance peptides | ||||||
Increase in AR (n = 6) | 1,168.64 | 22.7 | ||||
2,096.98 | 5.0 | |||||
1,828.85 | 3.0 | P12107 | COL11A1 | Collagen alpha-1 (XI-chain) | DGPPGPPGERGPQGPQGPV | |
2,176.00 | 1.8 | P25940 | COL5A3 | Collagen alpha-3(V) chain | QPGATGQPGPKGDVGQDGAPGIPG | |
968.58 | 1.7 | P07911 | UMOD | Uromodulin | SRVLNLGPI | |
1,468.81 | 1.5 | P07911 | UMOD | Uromodulin | VIDQSRVLNLGPIT | |
Decrease in AR (n = 5) | 1,082.70 | 20.3 | P61769 | B2M | B-2 microglobulin | IQRTPKIQV |
994.11 | 12.4 | |||||
1,438.80 | 3.1 | |||||
1,518.80 | 2.9 | P61769 | B2M | B-2 microglobulin | LSQPKIVKWDRDM | |
1,843.90 | 2.4 | P41222 | PTGDS | Prostaglandin-H2 D-isomerase | YSQGSKGPGEDFRMATL | |
Low-abundance peptides | ||||||
Increase in AR urine (n = 31) | 1,218.55 | 6.6 | ||||
1,717.79 | 5.6 | P17017 | ZNF14 | Zn Finger Protein | YQEYEKQPCKCKAV | |
2,008.94 | 5.3 | P25940 | COL5A3 | Collagen alpha-3(V) chain | ERGPPGSRGERGQPGATGQP | |
2,206.00 | 5.0 | P02452 | COL1A1 | Collagen Alpha-1(I) chain | ADGQPGAKGEPGDAGAKGDAGPPGP | |
1,202.55 | 4.8 | Q08174 | PCDH1 | Protocadherin-1 | EEQPPNTLIGS | |
1,235.52 | 4.4 | P25940 | COL5A3 | Collagen alpha-3(V) chain | QGVVGPSGPPGPPG | |
1,060.58 | 4.2 | |||||
1,322.61 | 3.6 | P25940 | COL5A3 | Collagen alpha-3(V) chain | GEPGPDGPPGRTGP | |
1,963.86 | 3.5 | O95498 | VNN2 | Vascular non-inflammatory molecule 2 | PQVNWIPCQDPHRFGH | |
1,992.97 | 3.1 | P25940 | COL5A3 | Collagen alpha-3(V) chain | IGPPGEAGEKGDQGLPGVQGP | |
1,028.54 | 2.8 | Q10586 | DBP | Albumin D box-binding protein | PGGAPLPPPPP | |
2,129.99 | 2.7 | P20908 | COL5A1 | Collagen alpha-1 (V) chain | DGPEGPKGRGGPNGDPGPLGPPG | |
1,614.83 | 2.6 | |||||
1,076.56 | 2.3 | O60909 | B4GALT1 | Beta-1,4-galactosyltransferase 2 | MSRLLGGTLE | |
1,160.55 | 2.2 | P25940 | COL5A3 | Collagen alpha-3(V) chain | PGQPGIRGPAGH | |
1,130.63 | 2.1 | P07911 | UMOD | Uromodulin | SVIDQSRVLN | |
1,101.52 | 2.0 | P39060 | COL18A1 | Collagen alpha-1 (XVIII) chain | PPGPPGPPGPPS | |
1,061.40 | 1.9 | |||||
2,466.12 | 1.8 | |||||
2,881.26 | 1.8 | |||||
1,047.48 | 1.8 | P07911 | UMOD | Uromodulin | SGSVIDQSRV | |
1,039.44 | 1.8 | |||||
2,327.02 | 1.7 | |||||
1,142.51 | 1.7 | P39060 | COL18A1 | Collagen alpha-1 (XVIII) chain | GPPGPPGPPGPPS | |
982.36 | 1.7 | |||||
1,117.47 | 1.6 | |||||
1,069.60 | 1.6 | P07911 | UMOD | Uromodulin | SRVLNLGPIT | |
2,636.20 | 1.5 | |||||
2,572.21 | 1.5 | |||||
2,236.10 | 1.5 | P27658 | COL8A1 | Collagen alpha-1 (VIII) chain | QDGIPGQPGFPGGKGEQGLPGLP | |
1,558.70 | 1.5 | P41222 | PTGDS | Prostaglandin-H2 D-isomerase | YSQGSKGPGEDFRM | |
Decrease in AR urine (n = 31) | 1,680.97 | 78.9 | P07911 | UMOD | Uromodulin | VIDQSRVLNLGPITRa |
2,604.30 | 35.2 | P61769 | B2M | B-2 microglobulin | LKNGERIEKVEHSDLSFSKDWS | |
1,615.90 | 14.8 | |||||
1,912.06 | 12.8 | P07911 | UMOD | Uromodulin | SGSVIDQSRVLNLGPITRa | |
956.53 | 8.9 | Q15654 | TRIP6 | Thyroid receptor-interacting protein 6 | QGRAIPRGT | |
1,303.70 | 8.5 | P02760 | AMBP | AMBP Alpha-1-microglobulin | YGRAPQLRETL | |
1,894.60 | 7.6 | |||||
1,663.60 | 6.1 | |||||
1,524.90 | 6.0 | P07911 | UMOD | Uromodulin | DQSRVLNLGPITR | |
1,854.00 | 5.6 | P25940 | COL5A3 | Collagen alpha-3 (V) chain | CLLLAALQLLPGTQADPV | |
2,436.20 | 5.0 | |||||
1,502.80 | 5.0 | |||||
2,436.20 | 5.0 | |||||
1,502.80 | 5.0 | |||||
1,631.90 | 4.5 | P61769 | B2M | B-2 microglobulin | LLKNGERIEKVEHSDL | |
982.61 | 3.6 | P07911 | UMOD | Uromodulin | VLNLGPITR | |
1,755.95 | 3.4 | P07911 | UMOD | Uromodulin | SGSVIDQSRVLNLGPITa | |
1,768.01 | 3.3 | P07911 | UMOD | Uromodulin | SVIDQSRVLNLGPITRa | |
1,654.91 | 2.8 | P07911 | UMOD | Uromodulin | SGSVIDQSRVLNLGPI | |
1,541.80 | 2.5 | |||||
1,188.70 | 2.4 | P01042 | KNG1 | Kininogen-1 | KRPPGFSPFR | |
1,204.60 | 2.2 | Q08174 | PCDH1 | Protocadherin-1 | EEQPPNTLIGS | |
2,040.16 | 2.2 | P07911 | UMOD | Uromodulin | RSGSVIDQSRVLNLGPITRa | |
1,204.70 | 2.2 | P25940 | COL5A3 | Collagen alpha-3 (V) chain | QPPVLGHGPRF | |
2,386.10 | 2.2 | |||||
1,578.70 | 2.0 | O75339 | CILP | Cartilage intermediate lauer protein | VGRCPVKTCAGQQDN | |
1,423.80 | 2.0 | P07911 | UMOD | Uromodulin | SVIDQSRVLNLGPI | |
1,736.90 | 2.0 | |||||
2,955.30 | 1.9 | |||||
2,311.00 | 1.6 | |||||
1,537.20 | 1.5 | |||||