Fig. 1

Principle component analysis using the 24 proteins that were found to change significantly with disease (p < 0.05) following two-way ANOVA. The first, second, and third principle component axes are indicated. Each individual subject is recognized by their respective ID number, and the spatial relationship between the individuals is shown along the three axes. A gender-dependent separation is apparent along the first principle component, whereas a condition-dependent separation is apparent along the second principle component