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Table 3 Polypeptide identifications

From: Confounding Effects of Benign Lung Diseases on Non-Small Cell Lung Cancer Serum Biomarker Discovery

m/z ratio

p value (Wilcoxon)

Fold change

Polypeptide identification

Experiment 1

Experiment 2

Experiment 1

Experiment 2

1,778

4.9 × 10−5

2.5 × 10−6

3.5

11

Fragment of complement C3f (SKITHRIHWESASLL)

1,865

6.5 × 10−4

2.4 × 10−7

2.1

46

Fragment of complement C3f (SSKITHRIHWESASLL)

3,273

4.2 × 10 −3

1.6 × 10−4

1.8

7.7

Fragment of ITIH 4 (MNFRPGVLSSRQLGLPGPPDVPDHAAYHPF)

3,289

9.8 × 10−6

1.4 × 10−4

2.4

8.9

Fragment of ITIH 4 (M*NFRPGVLSSRQLGLPGPPDVPDHAAYHPF)

5,080

1.6 × 10−8

4.1 × 10−3

1.7

2.2

Transthyretin fragment

6,431

5.1 × 10−3

2.0 × 10−2

0.67

0.63

N-terminal truncated apolipoprotein C1

6,631

2.5 × 10−4

3.5 × 10−3

0.55

0.60

Apolipoprotein C1

13,880

6.8 × 10−3

7.3 × 10−3

0.85

0.685

Transthyretin

14,070

1.3 × 10−3

3.5 × 10−4

0.71

0.64

Transthyretin

14,690

3.0 × 10−6

1.8 × 10−4

0.62

0.64

Lysozyme C

  1. p values are shown for cancer versus disease-free controls in SELDI experiments 1 and 2. Fold changes indicate the median of the cancer cohort divided by the median of the disease-free controls