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Table 2 Clinical data for patients chosen for the multiplex immunoassay

From: Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients

 

RD

SlD

N

p value

n, total

10

10

10

 

GFR 2004a (mL/min)

60.76 (11.3)

54.7 (7.9)

–

0.1051

ΔGFRa (mL/min) over 4 years

6.61 (1)

2.17 (1.6)

–

0.0002*

Age (years)

42.20 (8.3)

52.50 (9.2)

57.90(11.7)

0.0062*

Gender, %male

50

50

20

0.2987

Diabetes duration (years)a

27.90 (11.5)

37.10 (6)

41.40 (10.3)

0.017*

Systolic BP (mmHg)

137.4 (18.8)

133.0 (26.3)

138.1 (18.9)

0.9757

Diastolic BP (mmHg)

76.70 (9.5)

69.40 (16)

76.30 (11.4)

0.3859

BMI (kg/m2)

25.86 (4.2)

26.31 (6.5)

24.01 (1.7)

0.5544

HbA1C (%)

8.680 (1)

8.480 (1)

7.770 (0.8)

0.0822

Cholesterol (mmol/L)

4.660 (0.6)

4.920 (0.8)

5.030 (5)

0.5188

Triglycerides (mmol/L)

1.132 (0.4)

1.067 (0.3)

0.9870 (0.5)

0.5569

  1. Numbers are presented as mean (SD)
  2. n numbers, eGFR estimated glomerular filtration rate, BP blood pressure, HbA1c haemoglobin A1c
  3. *p < 0.05
  4. aNon-parametric data were evaluated by a Kruskal–Wallis F test or a Mann–Whitney test when only two values were compared