Urine Peptidomic and Targeted Plasma Protein Analyses in the Diagnosis and Monitoring of Systemic Juvenile Idiopathic Arthritis

Table 1 Patient characteristics—SJIA patient

Parameters	ND n = 2				SAF n = 18				AF n = 9				QOM n = 18				RD n = 9
Parameters	Obs.	Median	SD	Range	Obs.	Median	SD	Range	Obs.	Median	SD	Range	Obs.	Median	SD	Range	Obs.	Median	SD	Range
Age (year)	2	3	2.83	1–5	18	12.5	4.5	3–17	9	13	1.66	11–16	18	13	4.09	5–17	9	14	5.57	6–21
Gender (male%)	2		100%		18		33%		9		33%		18		39%		9		22%
WBC (103/ul)	2	14.6	3.96	11.8–17.4	18	13.05	7.87	4.3–38.5	8	7.25	4.41	5.9–18.7	17	5.9	1.36	4.2–8.4	5	5.6	2.07	4.1–9.6
ESR (mm/h)	2	54	8.49	48–60	16	47.5	27.36	5–108	7	9	5.19	0–17	17	5	9.06	0–29	6	5.5	1.47	38781
CRP (mg/dL)	1	29.4	NA	NA	13	12.2	28.96	1.8–82.7	5	0.2	3.72	0.2–8.6	8	0.8	3.22	0.2–9.7	4	0.3	0.38	0.2–1
PLT (103/ul)	2	480.5	102.53	408–553	18	492	168.99	226–829	8	338	112.79	222–520	17	333	61.87	216–426	5	301	30.62	292–367
NSAID (subjects%)	2		100%		16		88%		8		62%		14		86%		7		0%
PO.PRED (subjects%)	2		0%		16		50%		8		38%		14		29%		7		0%
MTX (subjects%)	2		0%		17		47%		8		50%		14		71%		7		0%
TNF (subjects%)	2		0%		16		12%		8		25%		14		50%		7		0%
IL.1.RA (subjects%)	2		0%		17		35%		8		12%		14		36%		7		0%

obs number of observations, SD standard deviation, NSAID nonsteroidal anti-inflammatory drug, PO.PRED PO prednisone, MTX methotrexate, TNF tumor necrosis factor, IL-1.RA interleukin 1 receptor antagonist

ISSN: 1559-0275