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Table 4 SJIA patient (flare and quiescent plasma samples) characteristics—patient demographics

From: Urine Peptidomic and Targeted Plasma Protein Analyses in the Diagnosis and Monitoring of Systemic Juvenile Idiopathic Arthritis

Parameters

SJIA F n = 25 (training)

SJIA Q n = 14 (training)

SJIA F n = 41 (bootstrapping testing)

SJIA Q n = 11 (bootstrapping testing)

Obs.

Median

SD

Range

Obs.

Median

SD

Range

Obs.

Median

SD

Range

Obs.

Median

SD

Range

Age (year)

24

9.00

4.04

2–16

14

10.00

4.08

2–16

22

9.00

4.17

2–16

9

10.00

5.34

3–19

Gender (male%)

25

 

60%

 

9

 

43%

 

19

 

58%

 

8

 

38%

 

WBC (103/ul)

25

13.90

5.75

8.1–32.6

14

7.10

2.21

4.2–11.6

35

14.00

9.00

4.8–38.5

11

6.80

3.20

4.2–12.6

ESR (mm/h)

24

96.50

36.36

10–143

14

10.50

6.43

2–24

31

80.00

34.38

6–131

8

9.00

6.45

7–25

CRP (mg/dL)

16

7.40

8.50

0.2–26.6

3

0.40

0.40

0.4–1.10

14

7.25

8.02

0.4–26.6

4

0.40

0.39

0.2–1.1

PLT (103/ul)

25

500.00

188.37

172–952

14

299.00

64.52

207–410

35

497.00

161.14

259–1085

11

293.00

50.07

216–355

NSAID (subjects%)

25

 

96%

 

8

 

57%

 

35

 

86%

 

11

 

73%

 

PO.PRED (subjects%)

25

 

48%

 

8

 

29%

 

35

 

66%

 

11

 

18%

 

MTX (subjects%)

25

 

16%

 

8

 

36%

 

35

 

40%

 

11

 

18%

 

TNF (subjects%)

25

 

16%

 

8

 

43%

 

35

 

37%

 

11

 

64%

 

IL.1.RA (subjects%)

25

 

4%

 

8

 

7%

 

35

 

6%

 

11

 

9%

 
  1. “Bootstrapping” differing from in silico bootstrapping (re-sampling) simulation, samples belonging to different visits of the same patient and even the same samples were assayed, i.e. “bootstrapped” experimentally
  2. Obs number of observations, SD standard deviation, NSAID nonsteroidal anti-inflammatory drug, PO.PRED PO prednisone, MTX methotrexate, TNF tumor necrosis factor, IL-1.RA interleukin 1 receptor antagonist