Urine Peptidomic and Targeted Plasma Protein Analyses in the Diagnosis and Monitoring of Systemic Juvenile Idiopathic Arthritis

Table 8 Identification of peptides found in normal plasma that are related to SJIA urine peptide biomarkers

MH+	Sequence	COL1A1 location
Urine peptide biomarkers
1,580.71	SpGSpGPDGKTGPPGpAG	543–560	COL1A1
Plasma peptides
1,723.80	LTGSpGSpGPDGKTGPPGp	540–558
1,266.59	SpGPDGKTGPpGpA	546–559
1,452.64	SpGSpGPDGKTGPpGP	543–558
1,436.65	SpGSPGPDGKTGPpGP	546–558
1,610.71	TGSpGSpGPDGKTGPpGP	541–558
1,594.72	TGSpGSPGPDGKTGPpGp	541–558
1,509.67	GSpGSpGPDGKTGPPGp	542–558
Urine peptide biomarkers
1,826.79	DEAGSEADHEGTHSTKR	605–621
1,883.8	DEAGSEADHEGTHSTKRG	605–622
Plasma peptides
1,354.52	DEAGSEADHEGTH	605–617	FGA
1,542.60	DEAGSEADHEGTHST	605–619
2,020.90	DEAGSEADHEGTHSTKRGH	605–623
2,091.92	DEAGSEADHEGTHSTKRGHA	605–624
2,560.20	DEAGSEADHEGTHSTKRGHAKSRP	605–628
2,659.24	DEAGSEADHEGTHSTKRGHAKSRPV	605–629
2,344.12	GSEADHEGTHSTKRGHAKSRPV	608–629
2,730.26	ADEAGSEADHEGTHSTKRGHAKSRPV	604–629
2,293.96	MADEAGSEADHEGTHSTKRGHA	603–624
2,762.25	MADEAGSEADHEGTHSTKRGHAKSRP	603–628
2,861.28	MADEAGSEADHEGTHSTKRGHAKSRPV	603–629
2,877.31	MADEAGSEADHEGTHSTKRGHAKSRPV	603–629
2,122.81	SYKMADEAGSEADHEGTHST	600–619
2,672.11	SYKMADEAGSEADHEGTHSTKRGHA	600–624
3,239.46	SYKMADEAGSEADHEGTHSTKRGHAKSRPV	600–629
3,255.46	SYKMADEAGSEADHEGTHSTKRGHAKSRPV	600–629
851.49	GHAKSRPV	622–629
Urine peptide biomarkers
1,631.83	EEAPSLRPAPPPISGGG	54–70	FGB
1,794.9	EEAPSLRPAPPPISGGGY	54–71
Plasma peptides
1,794.9	EEAPSLRPAPPPISGGGY	54–71
210.10	REEAPSLRPAPPPISGGGYR	53–72

ISSN: 1559-0275