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Table 2 A partial list of novel proteins upregulated in OA

From: Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients

  Gene symbol Protein Molecular function Cellular component Fold change (OA/RA)
1 CRISP3 Cysteine-rich secretory protein 3 Extracellular matrix structural constituent Secretory granule 5.0
2 TTK TTK protein kinase Protein threonine/tyrosine kinase activity Centrosome 5.0
3 NOTCH4 Notch 4 Receptor activity Plasma membrane 5.0
4 CD5L CD5 molecule-like Defense/immunity protein activity Extracellular 3.3
5 COL15A1 Collagen, type XV, alpha 1 Extracellular matrix structural constituent Extracellular 3.3
6 SSC5D Scavenger receptor cysteine rich domain containing (5 domains) Molecular function unknown - 3.3
7 RTN4RL2 Reticulon 4 receptor-like 2 Receptor activity Plasma membrane 3.3