Skip to main content
Figure 2 | Clinical Proteomics

Figure 2

From: Proteogenomic analysis of pathogenic yeast Cryptococcus neoformans using high resolution mass spectrometry

Figure 2

Schematic workflow of proteogenomic analysis. Mass spectrometry derived data was searched against protein database and six-frame translated genome database of C. neoformans var. grubii. Peptides mapping to the protein database confirmed annotated proteins and annotated splice junctions. C represents the number of peptides identified mapping to exons excluding A and B. Peptides unique to six-frame translated genome database were categorized based on their mapping to intergenic regions and regions within the annotated genes. These peptides were used to refine the annotation of genome.

Back to article page

Clinical Proteomics

ISSN: 1559-0275