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Table 1 Fold change (FC) of candidate markers in Set I and Set II* skin following SRM quantification

From: Quantitative tandem mass-spectrometry of skin tissue reveals putative psoriatic arthritis biomarkers

 

Set I

Set II

 

Lesional

Non-lesional

Lesional

Protein name

PsA:PsC FC **

P-value ***

PsA:PsC FC

P-value

PsA:PsC FC

P-value

CPN2

17.4

<0.001

2.4

0.030

1.9

0.032

GPS1

6.0

0.014

1.2

0.385

17.9

0.008

C16ORF62

6.0

<0.001

5.3

0.007

3.9

0.667

FHL1

4.6

<0.001

3.1

0.021

2.2

0.016

SRPX

3.8

0.043

3.3

0.014

5.0

0.008

SNCA

3.6

<0.001

1.7

0.089

3.8

0.095

POSTN

3.5

0.001

2.8

0.013

7.5

0.032

PAFAH1B2

3.3

0.004

2.0

0.104

0.8

0.667

SRP14

3.0

0.019

1.3

0.570

2.4

0.016

ITGB5

2.7

0.006

3.5

0.017

4.2

0.032

PPP2R4

2.2

0.043

2.0

0.678

3.9

0.008

LZIC

2.0

0.036

1.6

0.212

1.2

0.413

  1. *The description of Set I and Set II are given in the experimental methods section.
  2. **Fold change (FC) represents the ratio of means of 10 (Set I) or 5 (Set II) skin samples per group. Data are based on normalized XIC ratios, as described in the experimental methods section. PsA, psoriatic arthritis; PsC, cutaneous psoriasis.
  3. ***P-Values were calculated using the non-parametric Mann-Whitney U test.