Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns

Table 3 Pattern similarity following various depletion methods.

Method	Number of detected features	Number of common features in 3 replicates	Number of common features in 2 replicates	Number of features in only 1 replicate
IgY14	5478	1740 (31.8%)	1229 (22.4%)	2509 (45.8%)
IgYHSA	5446	1611 (29.5%)	1387 (25.5%)	2448 (45%)
Undepleted	4344	1465 (33.7%)	1124 (25.9%)	1755 (40.4%)

Table shows features (extracted and aligned with SuperHirn program) common to all 3 replicates in each depletion methods, those common to 2 replicates (excluding those common to the 3 replicates) and those found in only 1 replicate.

ISSN: 1559-0275