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Table 2 Selective ADAM inhibitors

From: The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?

Inhibitor Target ADAM Company Refs
INCB3619 10, 17 Incyte, Wilmington, DE [3234]
INCB7839 10,17 Incyte [34, 7072]
WAY-022 17 Wyeth-Aherst, Pearl River, NY [73]
GI254023X 10 Glaxo Smith Kline [74]
GW280264X 10,17 Glaxo Smith Kline [74]
TMI-2 17 Pfizer [75]
KB-R7785 12 Organon, Osaka, Japan [80]