From: The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?
Inhibitor
Target ADAM
Company
Refs
INCB3619
10, 17
Incyte, Wilmington, DE
[32–34]
INCB7839
10,17
Incyte
[34, 70–72]
WAY-022
17
Wyeth-Aherst, Pearl River, NY
[73]
GI254023X
10
Glaxo Smith Kline
[74]
GW280264X
TMI-2
Pfizer
[75]
KB-R7785
12
Organon, Osaka, Japan
[80]