Table 1 Significantly (p<0.0001) different mass peaks between benign and malignant cyst fluid samples, with ROC AUC >0.70 are listed with m/z value and identified peaks
From: Ovarian cyst fluid is a rich proteome resource for detection of new tumor biomarkers
Protein | Fraction | Peak m/z value | Mean intensity benign/malignant | ROC AUC | Specificity % (CI) |
|---|---|---|---|---|---|
PCI | EB-E3 | 3902 | 30.23 / 7.00 | 0.79 | 67.7 (58.9-75.6) |
ApoC-III | EB-E3 | 9743 | 3.60 / 15.09 | 0.82 | 68.5 (59.7-76.3) |
ApoC-III | EB-E3 | 9448 | 5.29 / 22.00 | 0.80 | 60.8 (51.8-69.2) |
ApoC-III | EB-E2 | 9751 | 4.65 / 24.2 | 0.80 | 60.8 (51.8-69.2) |
ApoC-III | EB-E2 | 9777.5 | 3.20 / 14.7 | 0.79 | 63.1 (54.2-71.4) |
ApoC-III | EB-E3 | 9453 | 7.30 / 33.20 | 0.78 | 50 (41.1-58.9) |
ApoC-I | MEP-M1 | 6647 | 37.53 / 121.14 | 0.78 | 57.7 (48.7-66.3) |
ApoC-I - truncated | MEP-M1 | 6448 | 68.91 / 184.53 | 0.76 | 53.1 (44.1-61.9) |
ApoC-I - truncated | MEP-M1 | 6489 | 24.49 / 52.75 | 0.76 | 53.1 (44.1-61.9) |
SAA4 | MEP-M1 | 12886 | 1.35 / 2.42 | 0.76 | 58.5 (49.5-67.0) |
SAA4 | MEP-M1 | 12863 | 1.53 / 2.72 | 0.74 | 59.2 (50.3-67.8) |
TTR | EB-E3 | 13900 | 7.80 / 23.16 | 0.77 | 59.2 (50.3-67.8) |
TTR | EB-E3 | 13925 | 5.36 / 14.27 | 0.75 | 57.7 (48.7-66.3) |
Hb beta | FT | 8037 | 2.61 / 4.64 | 0.75 | 65.4 (56.5-73.5) |
Albumin | FT | 54622 | 0.73 / 0.30 | 0.76 | 61.5 (52.6-69.9) |
Albumin | FT | 54426 | 1.72 / 0.25 | 0.75 | 60.8 (51.8-69.2) |
Albumin ion | MEP-M1 | 44754 | 1.06 / 0.50 | 0.76 | 57.7 (48.7-66.3) |