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Table 1 Significantly (p<0.0001) different mass peaks between benign and malignant cyst fluid samples, with ROC AUC >0.70 are listed with m/z value and identified peaks

From: Ovarian cyst fluid is a rich proteome resource for detection of new tumor biomarkers

Protein Fraction Peak m/z value Mean intensity benign/malignant ROC AUC Specificity % (CI)
PCI EB-E3 3902 30.23 / 7.00 0.79 67.7 (58.9-75.6)
ApoC-III EB-E3 9743 3.60 / 15.09 0.82 68.5 (59.7-76.3)
ApoC-III EB-E3 9448 5.29 / 22.00 0.80 60.8 (51.8-69.2)
ApoC-III EB-E2 9751 4.65 / 24.2 0.80 60.8 (51.8-69.2)
ApoC-III EB-E2 9777.5 3.20 / 14.7 0.79 63.1 (54.2-71.4)
ApoC-III EB-E3 9453 7.30 / 33.20 0.78 50 (41.1-58.9)
ApoC-I MEP-M1 6647 37.53 / 121.14 0.78 57.7 (48.7-66.3)
ApoC-I - truncated MEP-M1 6448 68.91 / 184.53 0.76 53.1 (44.1-61.9)
ApoC-I - truncated MEP-M1 6489 24.49 / 52.75 0.76 53.1 (44.1-61.9)
SAA4 MEP-M1 12886 1.35 / 2.42 0.76 58.5 (49.5-67.0)
SAA4 MEP-M1 12863 1.53 / 2.72 0.74 59.2 (50.3-67.8)
TTR EB-E3 13900 7.80 / 23.16 0.77 59.2 (50.3-67.8)
TTR EB-E3 13925 5.36 / 14.27 0.75 57.7 (48.7-66.3)
Hb beta FT 8037 2.61 / 4.64 0.75 65.4 (56.5-73.5)
Albumin FT 54622 0.73 / 0.30 0.76 61.5 (52.6-69.9)
Albumin FT 54426 1.72 / 0.25 0.75 60.8 (51.8-69.2)
Albumin ion MEP-M1 44754 1.06 / 0.50 0.76 57.7 (48.7-66.3)
  1. PCI = protein C inhibitor, ApoC-III = apolipoprotein C-III, ApoC-I = apolipoprotein C-I, SAA4 = serum amyloid A4, and TTR = transthyretin, EB = Equalizer Beads, differentially eluted yield fractions E2, and E3, MEP = Mercapto ethyl pyridine beads, differentially eluted yield fractions M1.