Serum biomarkers of Burkholderia mallei infection elucidated by proteomic imaging of skin and lung abscesses

Table 2 Serum calprotectin [μg/ml]

*Chlorocebus aethiops*	Collection day	Pre-exposure	Post-exposure ¹
1	5	1.45	>12.5*
2	11	1.09	>12.5*
3	13	0.70	>12.5*
4	14	1.89	7.27*
5²	28	2.27	10.55*
*Macaca mulatta*		Pre-exposure	Post-exposure
1	28	2.8	>25
2	28	3.2	16.8*
3	28	1.9	23.3*
4	28	1.5	21.9*
5	28	5.9	12.7*
*Macaca fascicularis*		Pre-exposure	Post-exposure
1	28	8.3	17.8
2	28	1.0	9.0*
3	28	1.5	6.4*
4	28	2.1	7.2*

¹Calprotectin concentration determined by ELISA, averaging the absorbance (450nm) of at least two technical replicates per primate and comparison to a standard curve.
²This was the only individual of this species surviving infection by aerosol exposure to B. mallei.
*: p ≤ 0.05.

ISSN: 1559-0275