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Figure 1 | Clinical Proteomics

Figure 1

From: Proteomics profiling identify CAPS as a potential predictive marker of tamoxifen resistance in estrogen receptor positive breast cancer

Figure 1

Putative tamoxifen predictive proteins. (A) Proteomics discovery workflow. (B) Score scatter plot from uni- and multivariate analysis, separating 12 matched pairs of control and relapse patients based on a 13 protein signature. Numbers indicate matched patient pairs. C (black) for control (>7 years of disease free follow up) and R (red) for relapse (within 2 years) patients. P = 2.2e-005. (C) Quantitative iTRAQ proteomics data showing the differences between control and relapse patients for the 13 proteins. Abbreviation: IPG-IEF, immobilized pH gradient – isoelectric focusing.

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Clinical Proteomics

ISSN: 1559-0275