Table 1 Proteins of human origin with unchanged total relative abundance levels that have up-regulated (italic text) or down-regulated (bold text) ubiquitylation levels in the luminal vs. basal xenografts
Protein | Accession | Protein function | Total protein relative abundance | Ubiquitylation site (relative abundance) |
|---|---|---|---|---|
NADPH-cytochrome P450 reductase [Homo sapiens] | 127139033 | Electron donation from NADPH to microsomal P450 enzymes | −1.20 | K613 (-2.47) |
bifunctional 3′-phosphoadenosine 5′-phosphosulfate synthase 1 [Homo sapiens] | 46094058 | Mediation of two steps in sulfate activation pathway | −1.29 | K194 (-2.44) |
ATP-binding cassette sub-family E member 1 [Homo sapiens] | 108773782 | Transport of molecules across extra- and intra-cellular membranes | −1.19 | K250 (-2.36) |
fatty acid synthase [Homo sapiens] | 41872631 | Catalysis of palmitate synthesis into long-chain saturated fatty acids | 0.80 | K1142 (2.46) |