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Table 1 Proteins of human origin with unchanged total relative abundance levels that have up-regulated (italic text) or down-regulated (bold text) ubiquitylation levels in the luminal vs. basal xenografts

From: Application of quantitative proteomics to the integrated analysis of the ubiquitylated and global proteomes of xenograft tumor tissues

Protein Accession Protein function Total protein relative abundance Ubiquitylation site (relative abundance)
NADPH-cytochrome P450 reductase [Homo sapiens] 127139033 Electron donation from NADPH to microsomal P450 enzymes −1.20 K613 (-2.47)
bifunctional 3′-phosphoadenosine 5′-phosphosulfate synthase 1 [Homo sapiens] 46094058 Mediation of two steps in sulfate activation pathway −1.29 K194 (-2.44)
ATP-binding cassette sub-family E member 1 [Homo sapiens] 108773782 Transport of molecules across extra- and intra-cellular membranes −1.19 K250 (-2.36)
fatty acid synthase [Homo sapiens] 41872631 Catalysis of palmitate synthesis into long-chain saturated fatty acids 0.80 K1142 (2.46)