From: Phosphotyrosine profiling of curcumin-induced signaling
Top functions (Networks) | Associated molecules | Score | Focus molecule |
---|---|---|---|
Cellular movement, cell morphology, cellular function and maintenance | Catenin, BAG3, BCAR1, BCR, c-Src, CAV1, CRK, CTNND1, DOCK1, EPHA2, F Actin, FAK,GAB1, Igm, LASP1, MLLT4, MYO1E, NFkB, p85, PDLIM1, PEAK1, PI3K p85, PLC gamma, PLCG1, PPP1CA, PPP1CB, PTPN6, PTPN11, Ras, Rock, SHC1, SLC9A1, TJP1, TJP2, TNK2 | 37 | 23 |
Cellular movement, cancer, cellular development | ADAM9, ANXA2, Ap1, AXL, BCAR3, calpain, CDH1, COL17A1, CTTN, EGFR, EPS15, ERBB2, ERK1/2, FAM120A, G protein alphi, INPPL1, IQGAP1, ITGB4, JAK2, Mapk, Mek, Mmp, PIK3R1, PTK2, PTPRE, PTPRK, Rac, Rap1, RIN1, SCAMP3, SDCBP, Shc, SRC,Vegf | 35 | 22 |
Cardiac arrythmia, cardiovascular disease, organismal injury and abnormalities | ARHGAP35, Cg, CLDN1, DSG2, DSP, ERK, ER, FLNB, FSH, FUBP3, Growth harmone, HDAC, HNRNPA1, HNRNPA2B1, HNRNPK, Hsp70, Hsp90, HSP90AA1, JNK, JUP, LDLR, LH, PCBP2, PCDH7, PKP2, PLIN3, Ras homologue, RASAL2, RNA polymerase II, Secretase gamma, SPTAN1, TNS3, TUBA1A, TUBA1C | 33 | 21 |
Cellular assembly and organization, cellular function and maintenance, cell-to-cell signaling and interaction | ABLIM1, Akt, ANXA1, CCDC88A, CD3, CFL1, CRKL, ERRFI1, Fibrinogen, G protein beta gamma, Gsk3, Hsp27, IgG, LDL, MAP2K1/2, MAPK1, MAPK3, MAPK13, MAPK14, NEDD9, P38 MAPK, PAG1, PDGF BB, PI3Â K (complex), PI3Â K (family), pkc, PP2A, PRKCD, PTK2B, SHANK2, STAT5a/b, SYK, TCR, VAV2, YES1 | 26 | 18 |
Embryonic development, hair and skin development and function, organ development | AHNAK, AIM1, CASP14, COL7A1, CTNNB1, EPHA1, EPHB2, ERBB2, ERBB2IP, ETV5, FOXQ1, GCHFR, GRB2, HENMT1, HNRNPA3, KRT5, KRT7, KRT14, KRT16, KRT80, NRCAM, OCIAD2, PABPC4, PHLDB1, PKP3, PKP4, QPCT, RPS17, SCG5, SCGB2A2, SHB, SMARCA4, STAT5A, TSPAN13, ZNF185 | 17 | 13 |