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Table 2 Insulin levels in 6 human serums tested by chemiluminescence immunoassays (CIA) and the developed immune-MS method

From: Immune-enrichment of insulin in bio-fluids on gold-nanoparticle decorated target plate and in situ detection by MALDI MS

  Serums of patients (accepting insulin therapy)
#1 #2 #3 #4 #5 #6
CIA (nM)a 1.0 3.6 3.2 2.1 3.5 2.3
MS (nM)b 1.3 3.8 3.3 2.2 3.8 2.4
  1. 5 Duplicates of each sample were tested by MALDI MS based on antibody-modified target plate and CIA
  2. a CIA chemiluminescence ImmunoAssays
  3. b MS MALDI MS based on antibody-modified target plate