Fig. 7From: Downregulation of ATP1A1 promotes cancer development in renal cell carcinomaSchematic summary of ATP1A1 roles in RCC development. The endogenous downregulation of ATP1A1 in RCC cells promotes the phosphorylation of c-Raf, MEK1/2 and ERK1/2, which affects ROS generation and increases cell growth and cell migration. RCC renal cell carcinoma. The means phosphorylationBack to article page