Downregulation of ATP1A1 promotes cancer development in renal cell carcinoma

Table 2 ATP1A1 immunoreactivity between RCTs and PKTs

Immuno-reactivity	RCTs (n = 80)			PKTs (n = 80)			P value
Immuno-reactivity	Percentage	Total score	Average score	Percentage	Total score	Average score	P value
Total	100% (80/80)	101.5	1.27 ± 1.85	100% (80/80)	668	8.35 ± 2.96
Negative	41.25% (33/80)	0	0 (−)	1.25% (1/80)	0	0 (−)	<0.05
Positive	58.75% (47/80)	101.5	2.16 ± 1.98 (+)	98.75% (79/80)	668	8.46 ± 2.83 (++)	<0.05

RCTs RCC tissues, PKTs para-cancerous kidney tissues
P value was calculated the differences between ATP1A1-positive RCTs and ATP1A1-negative PKTs using Student’ s t test. P < 0.05 was considered statistically significant
Negative: ATP1A1-negative expression with score 0; positive: ATP1A1-positive expression with score more than 0
−: Negative; +: low expression (the score was 1–4); ++: high expression (the score was over 4)

ISSN: 1559-0275