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Table 1 Demographics of the training and validation study populations

From: Clinical validation of a blood-based classifier for diagnostic evaluation of asymptomatic individuals with pulmonary nodules

  Training Validation
Control (n = 186) NSCLC (n = 95) CXR finding: nodule
Control (n = 119) Lung cancer (n = 119)
Gender
 Male 107 34 69 69
 Female 79 61 50 50
Age (years)
 Mean (SD) 62.3 (11.8) 66.5 (9.6) 63.7 (5.2) 64.4 (5.3)
Smoking
 Ever smokers 186 95 106 106
 Never smokers 13 13
 Pack years, mean (SD) 37.4 (21.5) 44.5 (21.3) 46.0 (32.4) 55.3 (40.9)
Abnormal suspicious finding
 Nodule NA NA 119 119
Stage
 I   95 (100%)   5 (4.2%)
 Ia    51 (42.9%)
 Ib    15 (12.6%)
 II    10 (8.4%)
 III    19 (16.0%)
 IV    14 (11.8%)
 NA    5 (4.2%)
Histology
 Adenocarcinoma   63 (66.3%)   57 (47.9%)
 BAC   4 (4.2%)   20 (16.8%)
 Squamous cell   15 (15.8%)   25 (21.0%)
 Large cell   6 (6.3%)   4 (3.4%)
 NSCLC   4 (4.2%)   2 (1.7%)
 Neuroendocrine   2 (2.1%)   2 (1.7%)
 Small cell    5 (4.2%)
 Adenosquamous   1 (1.1%)   4 (3.4%)